Sentence examples for mediate intercellular gene from inspiring English sources

Although it is clear that miRNAs function as a mechanism for post-transcriptional regulation, it has not been conclusively proven whether their presence in circulation is simply a by-product of cell degradation or whether are they actively secreted into the body fluids to mediate intercellular gene regulation.

Microvesicles from the plasma of patients with atherosclerosis containing higher levels of miR-150 were shown to effectively regulate migration and expression of miR-150 target gene c-MYB, demonstrating that circulating miRNA can mediate intercellular communication and regulate gene expression in an intracellular manner [ 29].

The secreted form of CyPA may mediate intercellular communication acting as an autocrine/paracrine factor.

Extracellular vesicles (EVs) are naturally occurring membrane particles that mediate intercellular communication by delivering molecular information between cells.

To elucidate the primary means through which EVs mediate intercellular communication, we characterized their ability to encapsulate and deliver different types of macromolecules from transiently transfected cells.

They bear surface receptors/ligands of the original cells and have the potential to selectively interact with specific target cells and mediate intercellular communication by transporting bioactive lipids, mRNA, or proteins between cells13,14.

aGPCRs have large alternatively spliced extracellular regions (ECRs) that likely mediate intercellular signaling; however, the precise roles of ECRs remain unclear.

MPs are small membrane-bound particles that originate from activated and dying cells and mediate intercellular communication.

Cell surface proteins mediate intercellular recognition and signal transduction.

For example, microvesicles may mediate intercellular communication by transporting bioactive lipids, mRNA, or proteins between cells.

Ephrins are cell-surface signaling molecules that bind in trans to Eph receptor tyrosine kinases to mediate intercellular communication.