SMRT contains two interacting domains that mediate interactions with nuclear receptors.
In one of the molecules of Vps25p in ESCRT-II these mediate interactions with Vps22p, and in the other molecule they interact with Vps36p.
Chromosome segregation requires assembly of kinetochores on centromeric chromatin to mediate interactions with spindle microtubules and control cell-cycle progression.
In Drosophila, NCenH3CID contains two other conserved motives that might also mediate interactions with kinetochore components.
First, we tested whether the homology between Lrig1 and Lrig3 is sufficient to mediate interactions with ErbB receptors.
In analogy, also exon 7 may therefore primarily mediate interactions with leucine zipper proteins other than FOXP3.
It is known that PLG kringle domains frequently mediate interactions with lysine residues of the bacterial receptors [20].
Thus, the first 50 amino acids (N50) of AR and the first 14 amino acids (N14) of Htt mediate interactions with F-actin in vitro.
Leptospiral surface components are thought to mediate interactions with host molecules, counteract host defense mechanisms, and promote the invasion and colonization of various tissues.
With the exception of SclZ.6, all of the CLPs have multiple short amino acid sequences (RGD, KGD, and GxPGER) that mediate interactions with integrins (Figure 6).
They both contain 4 WW domains that mediate interactions with proline rich motifs along with a C-terminus HECT domain responsible for E3 ligase activity.
