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Pulmonary DCs mediate inhalational tolerance which occurs during non-inflammatory settings through CCR7 dependent migration of pulmonary DCs to the draining bronchial lymph node[ 67].
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This study was designed to examine the endogenous CD8+ T cell response in a biphasic ovalbumin (OVA)–induced model of allergic airway disease (AAD) and its subsequent resolution with the development of local inhalational tolerance (LIT).
Our data establish an intriguing physicochemical mechanism whereby a bacterially-produced exoenzyme functions on the surface of another kingdom to directly mediate drug tolerance.
Our results suggested that LTP, DHN and PDF may mediate chilling tolerance in NM94 seedlings.
One potential therapeutic strategy for MS is to induce regulatory cells that mediate immunological tolerance.
More recently we have demonstrated that they also mediate maternal tolerance to the fetus.
Regulatory CD4+ T cells, which can transfer antigen-specific tolerance in an IL-10-dependent fashion, mediate the tolerance.
The inducible form of nitric oxide synthase may mediate the tolerance to ischemia.
Immune checkpoints are pathways that dampen inflammatory responses and mediate immune tolerance toward normal tissue.
Transcription factors (TFs) regulate plant abiotic stress responses and mediate stress tolerance [ 13].
Th17 cells are a subpopulation of CD4+ T cells that mediate inflammatory responses, while Treg cells are a type of negative immune regulatory cells that mediate immune tolerance.
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