Sentence examples for mediate inflammatory diseases from inspiring English sources

Genes encoding the highly polymorphic human leukocyte antigens (HLA) are known to mediate inflammatory diseases, immune disorders, infectious diseases, and human malignancies [11], [12].

Notably, activated macrophages can mediate inflammatory diseases during, for example, an acute infection (for example, sepsis) or via chronic autoimmune inflammation (such as atherosclerosis, rheumatoid arthritis or glomerulonephritis).

SAA is also known to possess proinflammatory properties and to mediate inflammatory disease pathogenesis [ 15, 16].

Infliximab (Remicade®) has been approved by use in patients with immune-mediate inflammatory diseases, such as Crohn's disease, rheumatoid arthritis, and psoriasis.

Immune-mediated inflammatory diseases (IMIDs) refer to a group of chronic conditions that share common inflammatory pathways [ 1].

Bradley, J. R. TNF-mediated inflammatory disease.

Multiple sclerosis (MS) is a genetically mediated inflammatory disease of the central nervous system (CNS) in which infiltrating immune cells lead to focal, demyelinating lesions1.

It has been previously shown that genetic or environmental factors, which promote susceptibility to allergic conditions, prevent the development of Th1-mediated inflammatory disease of multiple sclerosis (MS).

We explain how alterations to their profiles and functions under conditions of dysbiosis contribute to inflammation and effector immune responses that mediate inflammatory bowel diseases (IBD) in humans and enterocolitis in mice.

Experimental autoimmune uveitis [EAU] is a T cell mediated intraocular inflammatory disease that resembles human uveitis.

For example, it was observed that AQP4-specific antibodies promoted NMO-like pathologic changes within the CNS of rats with experimental autoimmune encephalomyelitis (EAE), a myelin-specific T-cell mediated CNS inflammatory disease.