Sentence examples for mediate inflammatory cascades from inspiring English sources

It was reported that the upregulated IL-6 and IL-1 may target the vascular endothelium to mediate inflammatory cascades, resulting in the aggravation of cerebral ischemic damage during the acute phase (Jafarinaveh et al., 2014).

pDCs are the main producers of type I IFNs, which mediate the inflammatory cascades in CLE.

There are also phenotypic similarities between articular cartilage chondrocytes, which mediate the inflammatory cascade in osteoarthritis, and NP cells, which mediate the cascade in the disc [ 27].

Moreover, macrophages present in the synovial fluid of OA express various receptors that mediate the inflammatory cascade [ 8].

The loss of Th1/Th2 balance in peripheral blood of ACS patients may represent distinct inflammatory cascades mediating the myocardial inflammation after myocardial necrosis which leads to ventricular remodeling [ 12].

Although we did not detect differences in NF-kB expression, we did observe decreased ephrinA1 expression in EphA2-R-M mice post-MI, and propose that the deficiency of EphA2-R prevents timely induction of inflammatory cascades necessary for mediating repair.

Platelets mediate inflammatory responses by facilitating immune cell crosstalk and participating in inflammatory signalling cascades.

The initiation stage is mediated by proteolytic degradation of extracellular matrix proteins attributable to increased HTRA1 activity, whereas the progression stage is driven by inflammatory cascades.

More recently, inflammatory cascades were thought to be at the root of lesion development.

Platelet activating factor (PAF) interacts with cell surface receptors to mediate inflammatory responses.

This is thought to be secondary to their anti-inflammatory effect, blocking inflammatory cascades triggered in sepsis [2, 3].