Sentence examples for mediate inclusion of from inspiring English sources

Taken together, these data indicate the extensive use of NOVA in steady-state neurons to inhibit cryptic NMD exons, and, to a lesser degree, mediate inclusion of NMD exons, as a means to maintain or reduce, respectively, the steady-state levels of neuronal transcripts and proteins.

We also rewrote relevant text, as in the following (which previously referred to "widespread"): "Taken together, these data indicate the extensive use of NOVA in steady-state neurons to inhibit cryptic NMD exons, and, to a lesser degree, mediate inclusion of NMD exons, as a means to maintain or reduce, respectively, the steady-state levels of neuronal transcripts and proteins".

IncA is so far the best characterized Inc protein and has been shown to mediate inclusion fusogenicity through interaction of its soluble N-ethylmaleimide-sensitive-factor attachment receptor (SNARE) like cytoplasmic coiled-coil domains forming tetramer bundles [ 116- 119].

Post-ER trafficking is mediated by inclusion of correctly folded polypeptides into vesicles at the transitional ER (tER) [13].

It seems likely, therefore, that each paralog mediates the inclusion of specific cargo proteins into vesicles for subsequent export from the ER.

Therefore, a potential mechanism by which miR-1 may regulate Myocd splicing is through the direct repression of a splice factor that normally mediates alternate inclusion of the 2a exon in smooth muscle.

Taken as a whole, the enhancement of IL-10 expression, and reduction in iNOS and IFN-β expression, mediated by the inclusion of mosquito saliva during WNV infection, constitute a significant alternation in the early antiviral response.

Furthermore, the per-protocol analysis revealed this effect is mediated by the inclusion of a GP's signature on the endorsement letter.

They employed a splicing variant-specific form of the co-immunoprecipitation assay to demonstrate the extensive and tissue-specific rewiring of protein interaction networks mediated by the inclusion of specific alternative exons.

The effects of social caste and education were attenuated in the mutually adjusted model (model 4), suggesting that their independent effects on self-reported diabetes were at least partially mediated by the inclusion of household in this model.

This switchback in the splicing profile is associated with robust rescue from hnRNPH-induced cell death in both cell types, indicating that hnRNPH not only significantly promotes cell survival, but also that its action is specifically mediated by inhibiting inclusion of IG20 exon 16.