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The different expression patterns of the novel miRNAs over the life stages of S. japonicum suggest that they may mediate important roles in Schistosome growth and development.
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PP1βMYPT1 has also been implicated in mediating important roles in the cell cycle, by dephosphorylating PLK1 as well as other proteins predicted to regulate kinetochore, centrosomes and central spindle [ 14, 51].
TGF-β signaling, which is mediated by TGFBR1, plays important roles in the developing liver and throughout adulthood.
Recently, it was found that Mediator Complex Subunit25 (mediatesT1) mediates JA signaling and plays important roles in resistance to necrotrophic fungal pathogens.
Intriguingly, p53 played important roles in mediating the p38-mediated regulation of eIF2 α and eIF4E.
In conclusion, our results demonstrated that in vitro UCP2 plays important roles on mediate ROS production, apoptotic process, and steroidogenesis.
CTLs play important roles in mediating cell adhesion and the recognition of pathogens in the immune system.
Long-range (hormones) and short-range signalling molecules play important roles in mediating cell cell maternal interactions/communications with gametes and embryos.
We have previously demonstrated that versican plays important roles in mediating cell activities [46],[46].
Since these modifications are highly synchronized, HATs and HDACs play important roles in mediating these changes.
Once activated, these pathways play important roles in mediating EGFR effects on cellular proliferation and survival.
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