Sentence examples for mediate gene silencing from inspiring English sources

Different classes of small RNAs (sRNAs) refine the expression of numerous genes in higher eukaryotes by directing protein partners to complementary nucleic acids, where they mediate gene silencing.

In different systems, PRC2 and PRC1 appear to cooperatively mediate gene silencing.

Consistent with this result, immunocytochemistry experiments showed that MBD5 localizes to non-heterochromatin regions of the nucleus, in contrast to heterochromatin-associated MeCP2, an MBD family member known to mediate gene silencing.

MicroRNAs (miRNAs) are prevalent regulatory RNAs that mediate gene silencing and play key roles in diverse cellular processes.

Laible, G. et al. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.

Laible, G., et al. Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisae telomeres.

Lyons, D.B. et al. Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons.

RNA interference (RNAi) refers to double-stranded RNA (dsRNA) mediated gene silencing [1].

As the data implied that the Polycomb-targeted gene profile would be highly relevant for pharmacological treatment of MM, we used two compounds to chemically revert the H3K27-tri-methylation mediated gene silencing.

Hypermethylation of tumour suppressor genes is associated with epigenetically mediated gene silencing.

Post-transcriptional regulation in eukaryotes can be operated through microRNA (miRNAs) mediated gene silencing.