Sentence examples for mediate gene activation from inspiring English sources

MBD2 may also mediate gene activation because of its potential DNA demethylase activity.

A recent finding also suggests that MBD2 has potential DNA demethylase activity [ 13], implying that it might mediate gene activation in addition to transcriptional repression.

Many, if not most, cytokines use the Janus kinase (Jak)–signal transducer and activator of transcription (STAT) signaling pathway to mediate gene activation or repression.

When p97 is inhibited, Nrf1 is not retrotranslocated, and the carboxy-terminal domain, which contains the sequences that mediate gene activation, remains in the ER lumen.

As these regions are largely already bound by C/EBPβ in pre-adipocytes, it is possible that ZEB1 specifically relocates there upon differentiation induction to mediate gene activation.

Therefore, we analysed the 2 kb upstream promoter fragment to identify candidate transcription factor-binding sites that could mediate gene activation during differentiation.

Studies with cultured cells using the WNT activated TOPFLASH promoter have identified many components that contribute to WNT mediated gene activation.

Jiao, A. L. & Slack, F. J. RNA-mediated gene activation.

ROS can directly reinforce passive barriers against pathogens - for example by chemically modifying plant cell walls - but are also important signal molecules mediating gene activation [28], [29].

A specific cis-acting element of gene enhancer in CYP3A4 has also identified which confers HNF4α binding and permits PXR- and CAR-mediated gene activation [ 22].

Both MLL3 and MLL4 are part of the ASCOM complex and have an important role in NR-mediated gene activation (Lee et al, 2008b; Ansari and Mandal, 2010).