Sentence examples for mediate fusion of from inspiring English sources

HIV-1 Env mediates fusion of viral and target cell membranes, but it can also mediate fusion of infected (producer) and target cells, thus triggering the formation of multinucleated cells, so-called syncytia.

Recent structural advances reveal how very different protein architectures can be used to form trimeric extensions that extend into the target cell membrane and then fold back to mediate fusion of the target and viral membranes.

Recent evidence suggests that members of the SNARE family mediate fusion of cytotoxic granules with the surface of CTLs.

This process will expose the hydrophobic fusion peptide and mediate fusion of the viral envelope with the host cell membranes [56].

For example, COG7 (PPI = 8, CC = 0.43 and fitness pleiotropy = 6) encodes a component of the cytosolic Golgi tethering complex that functions to mediate fusion of transport vesicles to Golgi compartments [24].

Our next question is, therefore, which SNARE proteins mediate fusion of recycling vesicles with the PM downstream of the exocyst.

To address the possibility that EXO1 participates in LIG3-dependent A-NHEJ reactions to mediate fusions of uncapped telomeres, we inactivated LIG3 and EXO1 using shRNAs in cells lacking TRF2.

GP1 mediates host cell attachment and receptor recognition, whereas GP2 mediates fusion of the viral and host membranes8,9,10,11,12.

In the present study, we found that ULK1 mediates fusion of the autophagosome to the lysosome by interacting with STX17.

The fusion (F) protein mediates fusion of viral and cell membranes and is highly conserved.

The HA is also responsible for cell entry by mediating fusion of the endosomal and viral membranes.