Sentence examples for mediate expression of from inspiring English sources

Integrin β1 was shown to mediate expression of FAK in lung cancer cells, with proliferation following metastasis dependent on β1 and FAK expression levels [44].

Moreover, RIM1 confers sustained activity and neurotransmitter vesicle anchoring to pre-synaptic Ca2+ channels [50], which mediate expression of pre-synaptic LTP [51].

Infecting Müller glia, a cell that is accessible from the vitreous and transverses the entire thickness of the retina, would be ideal to mediate expression of secreted neurotrophic or anti-angiogenic factors throughout all layers of the retina (Fig. 1).

To overcome these issues, we describe here a Cre-transgenic line that can mediate expression of multiple Cre-dependent transgenes of choice in very few neurons of the adolescent neocortex, hippocampus, olfactory bulb, striatum, amygdala, hypothalamus and superior colliculus.

Examples include thousands of promoter CpG islands for which methylation appears to mediate expression of genes in a tissue- and lineage-specific fashion, and DMRs associated with dozens of imprinted genes for which parent-of-origin DNA methylation marks are believed to mediate monoallelic expression in somatic cells.

These data indicate that GFP is present on the surface of KAHRP-GFP-Cter, Rifin-GFP-Cter, Stevor-GFP-Cter, and Pb-GFP-Cter infected erythrocytes, and thus these N-termini together with the C-terminus of PfEMP1 mediate expression of PfEMP1 on the surface of P. berghei-infected erythrocytes.

Overall, Pten can be directly linked to the extrinsic apoptotic pathway through mediation of TNFα signaling and the intrinsic apoptotic pathway by mediating expression of mitochondrial apoptosis factors.

NF-κB activation mediates expression of inflammatory genes, in term induces cell apoptosis.

Apart from its stimulatory effect on LEE, grlA also mediates expression of non-LEE encoded effectors [25].

CREB mediates expression of a high number of genes that are implicated in a wide array of cell functions, including transcription, cell cycle, and immune regulation [41], [50].

In addition, up-regulation of miR-31 mediates expression of the non-canonical ligand Wnt5a, which induces epithelial-to-mesenchymal transition (EMT), and dramatically enhances the malignant phenotype of lung cancer cells (Ripley et al, submitted for publication).