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This process also appears to mediate expansion of root hairs (Hachez et al. 2014), which are cells well known for showing SNARE-dependent polarized tip growth (Larson et al. 2014).
In contrast, early inhibitors, even those with lower potency, are predicted to exert a systemic antiviral effect and to be able to mediate expansion of transduced cells able to resist HIV infection.
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For example, parathyroid hormone receptor activation can increase the number of osteoblastic cells, resulting in Notch1-mediated expansion of HSCs [8].
21, 22 In particular, IL-7 mediates expansion of early thymocyte progenitors, whereas IL-15 plays a role in NK cell development.
The results of the present study indicate that the signalling cascades mobilised by both Met2P and Met2S receptors equivalently allow triggering of the production by pioneer neurons of this signal mediating expansion of Pea3 expression to recruited neurons.
Recently, two studies suggested that a dermal DC subset may be involved in psoriasis initiation via the production of IL-23 (Wohn et al, 2013), a key cytokine that mediates expansion of IL-17- and IL-22-producing cells, promoting important events in psoriasis pathology, including neutrophil infiltration and epidermal thickening (Di Cesare et al, 2009).
Whether Noxa also mediates expansion capacity of other cells within the hematopoietic lineage such as erythroblasts is currently unknown.
Moreover, serotonin has been previously shown to mediate compensatory expansion of the β cell during pregnancy (Kim et al., 2010).
When Alu sequences are near or at the boundaries of the duplication units they are known to mediate the expansion of segmental duplications through recombination.
Additionally, shh hyper expression was shown to increase jaw width and taste bud number, and to mediate the expansion of the forebrain and hypothalamus [ 11, 22].
So far, there are few reports that vesicle-free forms associated with protein or HDL complexes can mediate the expansion of cancer malignancy in an autocrine or paracrine manner [ 25].
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