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They contribute to the uptake of nutrients and can mediate essential functions during the infection cycle.
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Such over-expression of SOCS genes is thought to be a specific lesion in breast cancer tissue cells which may provide resistance to pro-inflammatory and trophic cytokines through blocking STAT signaling which mediates essential functions in the mammary tissue, and may well be implicated in mammary oncogenesis [ 47].
On one hand, RBPs assist the processing and assembly of non-coding (nc) RNAs into RNP complexes, which mediate essential cellular functions such as splicing and translation [1].
Telomere sequence DNA repeats are bound by a set of proteins that mediate two essential functions: first, to protect the ends from degradation, recombination, and initiation of a damage response and second, to regulate telomere elongation by telomerase.
Neurons mediate many essential functions in the body such as maintaining a state of consciousness and mental arousal.
This genetic approach is ideal to assess whether the Thr668 mediates the essential functions of APP.
The paralogs may present alternative routes by which parasite lines carrying different pfcrt alleles could mediate this essential function.
Monocytes are bone marrow-derived cells that mediate essential regulatory and effector functions in innate and adaptative immunity [ 6].
Monocytes are bone marrow-derived cells that mediate essential regulatory and effector functions in innate and adaptive immunity [ 32].
A variation of this scenario is depicted in Case IV for independent, parallel survival pathways wherein one serves as a compensatory pathway in the absence of the other to mediate a common, essential function.
This interferes with the chaperones' essential functions of mediating folding of essential proteins.
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