Sentence examples for mediate elimination of from inspiring English sources

Certain immune cells such as neutrophils mediate elimination of foreign organisms such as bacteria and fungi with superoxide that is produced by NADPH oxidases located on the cell membrane [29].

Therefore, the downregulated miR-29 may regulate the T helper 1 (Th1) cell differentiation to secrete more IFN-gamma and mediate elimination of intracellular pathogens, but dysregulated T cell responses may also contribute to pathologic inflammation.

We reasoned that the pi-RISC, by virtue of the enormous sequence portfolio of piRNAs, might mediate elimination of a large variety of mRNAs in late stages of spermiogenesis.

Our results show the genetic mechanism through which cell selection mediates elimination of suboptimal but viable cells.

Additionally, the growth medium for ZR-75-1 wasupplementeded with 1 nM β-estradiol (Sigma-Aldrich), and did not contain sodium pyruvate, which mediates elimination of H2O2 from the culture medium [ 21].

The binding of activated platelets to tumor cells has been shown to hinder natural killer cell mediated elimination of circulating tumor cells [ 21], and the destruction of circulating platelets with antiplatelet antibodies significantly reduces metastatic potential in several murine tumor models [ 22].

41,54,55 Salivary and fecal IgA are considered to represent the common mucosal immune response (secretory IgA) that can prevent initial pathogen entry, while circulating IgA and IgG form a second line of defense, mediating elimination of pathogens that have breached the mucosal surface.

The interaction of the adhesion molecule of the immunoglobulin family intercellular adhesion molecule 1 (ICAM-1) with its ligands such that the integrins LFA-1 and Mac-1 is crucial for the regulation of several physiological and pathophysiological processes like cell mediated-elimination of tumor or virus infected cells, cancer metastasis or inflammatory autoimmune processes.

The efficiency of scavenger receptors depends on their capability to mediate the elimination of a stoichiometric multiplicity of ligands from the surrounding environment.

Most CTL expressing antigen specific receptors (TCRs) mediate the elimination of tumor cells by recognition of antigen in the form of individual peptides bound to MHC molecules [ 23, 24].

In the literature, two main processes have been described to mediate the elimination of unfit/polarity-deficient cells from Drosophila imaginal epithelia: Cell Competition (CC) and Intrinsic Tumour Suppression (ITS) [ 9].