Sentence examples for mediate effective from inspiring English sources

We have, however, shown that the AF C system has an insufficient capacity to mediate effective C-mediated tumour cell killing.

Interestingly, these antibodies only neutralize HIV-1 weakly, but mediate effective antibody-dependent cell-mediated cytotoxicity (ADCC) as the mechanism to thwart HIV-1.

This chapter focuses on providing information for the design of constructs that mediate effective silencing.

Although the interaction of tetramers is diffusion controlled, it is strongly driven by their geometry to mediate effective subunit targeting.

This investigation would shed light on the deliberate design of oral shRNA delivery vehicles to mediate effective antitumor efficacy.

The chapter also provides the first evidence that Cre recombinase can mediate effective site-specific deletion of transgenes in zebrafish.

FA-PPI mediated effective transfection of the TNF-related apoptosis-inducing ligand gene (TRAIL) in human hepatoma Bel 7402 cells, leading to cell apoptosis and great suppression of cell viability.

We provide evidence and mechanistic insight that CXCR7 acts as specific scavenger for CXCL12 and CXCL11 mediating effective ligand internalization and targeting of the chemokine cargo for degradation.

These results indicate that blocking L-type and R-type VGCC in DCs activated T cells that subsequently mediated effective killing of virulent M. tuberculosis inside macrophages.

To determine whether the convergent U6/H1 expression cassette could produce functional siRNA that mediated effective gene suppression, an insert encoding a p53-specific siRNA [6] was enzymatically-generated (as described in materials and methods) and cloned into pHybrid (Figure 1A).

Importantly, conditioning CFP10-DCs with either RANTES and IP-10 or IFN-γ and IL-12 mediates effective clearance of an established M. tb infection in mice, thereby giving functional relevance to the above observations.