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While generic CC stretches are encountered in a very wide range of proteins, there are certain well-conserved versions of the CC with characteristic sequence features, which mediate distinct types of interactions [ 20].
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It is possible that the two presenilins mediate distinct cell type specific functions in the CNS.
The recognition of pathogen effectors triggers an innate immunity response that is mediated by two distinct types of NB-LRR proteins, the toll-interleukin-1 receptor (TIR -NB-LRR proTIR -NB-LRRhe coiled-coil (CC)-NB-LRR proTIR -NB-LRR
Receptor tyrosine kinases (RTKs) signal through shared intracellular pathways yet mediate distinct outcomes across many cell types.
It is currently unknown whether atlastins and the SNAREs involved in ER fusion, such as syntaxin 18 (Hatsuzawa et al. 2000), act cooperatively to form and maintain the membrane network of the ER or whether they mediate distinct fusion events on different types of membranes.
5-HT mediates its actions through 14 distinct types of receptors encoded by a respective number of genes and its actions outnumber by far those of any other neurotransmitter.
Two main types of DCs that mediate distinct biological outcomes are distinguished by their lineage origin: myeloid DCs and plasmacytoid DCs.
Studies with cholinergic receptor blocking agents and protein kinase C inhibitors indicated two distinct types of effects, one mediated through stimulation of nicotinic cholinergic receptors and the other targeting intracellular signaling.
Some SG-resident proteins mediate distinct cellular responses to stress that are dependent on the type of stress encountered 49505151.
Through specific interactions with distinct types of Fcγ receptors (FcγRs), the Fc domain of immunoglobulin G (IgG) mediates a wide spectrum of immunological functions that influence both innate and adaptive responses.
Differences in the composition of complexes between adaptor molecules and other proteins, mediated by specific protein interaction domains, could underlie different types of synaptic plasticity found in distinct types of neuron.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com