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Receptor tyrosine kinases (RTKs) signal through shared intracellular pathways yet mediate distinct outcomes across many cell types.
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Two main types of DCs that mediate distinct biological outcomes are distinguished by their lineage origin: myeloid DCs and plasmacytoid DCs.
Looping events have been observed to be mediated by distinct transcriptional factors[51], which may confer the loops different regulatory functions and generate distinct outcomes.
Weighing these factors, I can envision two distinct outcomes for Russian democracy.
It is possible that the two presenilins mediate distinct cell type specific functions in the CNS.
Different forms of ERs mediate distinct functions of E2.
Conversely, a given growth factor receptor can employ distinct signalling effector pathways to mediate distinct cellular responses.
Individual TLRs mediate distinct responses by association with a different combination of adaptor molecules.
It is likely that these regions mediate distinct but complementary mechanisms in the support of recollection.
In mammals, complexes of mTOR with RAPTOR (TORC1) and RICTOR (TORC2) mediate distinct signalling pathways.
CsA differentially inhibited signaling pathways which mediated distinct steps of the angiogenic process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com