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Raf and akt mediate distinct aspects of sensory axon growth.
These genes may mediate distinct aspects of the process, from intracellular signaling (such as hypodermal-specific transcription factors) to extracellular execution (such as cuticle-digesting proteases).
In these cells, IRS proteins are required for and mediate distinct aspects of IGF-IR-stimulated behaviour.
In addition to temporal differences in activation, these transcription factors also have been shown to mediate distinct aspects of drug addiction.
Herein, we sought to determine whether IGF-IR requires IRS-1 and -2 to transduce its biological effects, and whether these IRS proteins mediate distinct aspects of IGF-IR action in breast cancer cells.
Furthermore, to determine whether IRS-1 and -2 mediate distinct aspects of IGF-IR biology, we stably expressed IRS-1 or -2 proteins in T47D-YA cells and examined biological responsiveness.
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In addition, these differences indicate that Ap4 is responsible for mediating a distinct aspect of c-Myc function and does not simply perform all functions of c-Myc.
What distinct aspects of vision are mediated by different cell types?
Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking.
The action of transcriptional repressors is heterogeneous and can exhibit context effects; one of the most striking aspects involves the different classes of repressors that mediate distinct chromatin changes on target genes.
In the lung, how TFs interact with each other and signaling molecules to regulate groups of gene targets mediating distinct but integrated aspects of cell or organ function, and how lipid homeostasis is integrated with maturation of type II epithelial cells remain unclear.
More suggestions(15)
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mediate various aspects
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