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Our primary finding is that TLR5 and NLRC4 mediate different roles in the inflammatory response to Lp flagellin in an aerosolized infection model.
These studies reveal that NLRC4 and TLR5 mediate different roles in the inflammatory response to Lp flagellin in an aerosolized infection model and NLRC4 regulates replication in both lungs and alveolar macrophages.
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Thus, in addition to its requirement for cell viability, Ras appears to mediate different biological roles depending on the developmental context and on the level of its expression.
Thus, firing rates do not reflect the predicted inhibitory excitatory imbalance across the motor thalamus, and input zone-specific temporal coding through oscillatory synchronization with the cortex could partly mediate the different roles of basal ganglia and cerebellum in behavior.
It is already known that, in TUs, discoordinate expression occurs when the product of an individual gene needs to be expressed apart from the others to mediate a different role.
Fibronectin serves different roles mediated by distinct domains and isoforms.
Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans.
It has been shown that neurabin and spinophilin play different roles in mediating behavioral responses to cocaine administration [20].
However, this interaction appears to play different roles in mediating quinolone activity in different species.
Ang-1, Ang-2, and Tie-2 play different roles in mediating vascular quiescence and inflammation.
Despite the importance of the bridge, it appears to play different roles in mediating quinolone activity against B. anthracis and E. coli topoisomerase IV.
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CEO of Professional Science Editing for Scientists @ prosciediting.com