Sentence examples for mediate contacts with from inspiring English sources

While these various specializations likely mediate contacts with other cells or substrates, their functions and mechanisms are of course at this point unclear.

The active site of the deoxyribonuclease (DNase) activity is also required for ribonuclease (RNase) activity of BGLF5 in vitro [8], although the identification of single function mutants that retain DNase activity and lack shutoff and vice versa [3], [9] indicates that additional residues mediate contacts with viral or cellular factors, or the nucleic acids themselves, to specify the substrate.

DOI: http://dx.doi.org/10.7554/eLife.00327.009 Many hydrophobic and aromatic residues in CycT1 mediate contacts with AFF4.

Reports showed that at least one selectin (P, L, or E) is capable of binding to any human carcinoma, which demonstrates the potential of selectins to mediate contacts with tumor cells within vasculature.

However, because P110 lies in the 'latching loop' region of eukaryotic Mre11 that is likely to mediate contacts with Xrs2 (Schiller et al, 2012), sae2Δ suppression by this mutation might arise through altering such contacts.

In this regard, we note that the site of one of the sae2∆ suppressors, P110, lies in the 'latching loop' region of eukaryotic Mre11 that is likely to mediate contacts with Xrs2 (Schiller et al, 2012), suggesting that, in this case, sae2Δ suppression might arise through weakening this interaction and dampening Tel1 activity.

These results reinforce the importance of the perturbation ΔF508 causes in the surface topography of NBD1 in a region likely to mediate contact with the transmembrane domains of CFTR.

Nasal vaccination is known to induce serum IgG due to the capacity of mucosal immune cells (e.g. DCs, B cells) to activate and effectively mediate contact with systemic immune sites [35].

The main role for T4SSs is to translocate virulence factors to hosts and to promote DNA transfer [7], while the role of the pilus [28] [30] is to mediate contact with host receptors and function as a DNA secretion channel.

The export receptors in turn mediate contact with the NPC and are essential for translocation of the mRNP through the NPC.

Rely on meant for the FP to trust the DN to carry out investigations and treatment initiated by the FP, to inform the FP and mediate contact with patients when asked.