These results suggest that hemagglutinins mediate contact between bacterial cells impairing X. fastidiosa movement in the plant xylem and thus reducing virulence [8].
PfEMP-1 molecules are concentrated on knob-like protrusions that mediate contact between parasitized RBCs and MVECs or monocytes [14], [27].
A heterodimer may mediate contact between two CIK cells and two tumor cells at most.
Another feature of HEAT repeats is the presence of conserved polar residues near the surface inter-helix loop, which mediate contact between the two helices [13].
Anti-CD3 × anti-HER2 BsAb is designed to mediate contact between cytotoxic T cells and tumor cells expressing high levels of HER2; thus, anti-CD3 × anti-HER2 dimers are the ideal effectors.
These data suggest that NTN1, signaling though NEO1, maintains the integrity of the end bud by mediating contacts between cap and luminal epithelial cells, and these contacts are required for robust forward growth of the mammary tree.
Cadherin-11 has been identified as a key regulator of synovial architecture mediating contact between Fibroblast-like Synoviocytes and organization in the lining layer.
The binding of these ligands to CCR4 helps to guide Tregs towards DC, mediates contact between these two cell types and thus inhibits activation of DC and the DC-mediated T cell response.
IFT relies on a large 20-subunit protein complex that is thought to mediate the contacts between ciliary motor and cargo proteins.
