Sentence examples for mediate contacts from inspiring English sources

In the parasite protein, several salt-bridges mediate contacts between the subunits whereas in the human enzyme these interactions are mainly of hydrophobic nature.

While these various specializations likely mediate contacts with other cells or substrates, their functions and mechanisms are of course at this point unclear.

The active site of the deoxyribonuclease (DNase) activity is also required for ribonuclease (RNase) activity of BGLF5 in vitro [8], although the identification of single function mutants that retain DNase activity and lack shutoff and vice versa [3], [9] indicates that additional residues mediate contacts with viral or cellular factors, or the nucleic acids themselves, to specify the substrate.

DOI: http://dx.doi.org/10.7554/eLife.00327.009 Many hydrophobic and aromatic residues in CycT1 mediate contacts with AFF4.

On one face of the G-box β-sheet strings of hydrophobic residues, such as Val, Val and Ile, mediate contacts between adjacent strands.

Specifically, motif 2 from each CTD protomer combine to mediate contacts to one intercalated c-di-GMP dimer, Asp116 of motif 1 from each protomer combine to mediate contacts to the other c-di-GMP dimer, while Arg114 sits centrally and anchors both dimers.

These results reinforce the importance of the perturbation ΔF508 causes in the surface topography of NBD1 in a region likely to mediate contact with the transmembrane domains of CFTR.

Among these genes DDR2 [51] has previously shown to mediate contact inhibition of cancer cells.

These results suggest that hemagglutinins mediate contact between bacterial cells impairing X. fastidiosa movement in the plant xylem and thus reducing virulence [8].

PfEMP-1 molecules are concentrated on knob-like protrusions that mediate contact between parasitized RBCs and MVECs or monocytes [14], [27].

Nasal vaccination is known to induce serum IgG due to the capacity of mucosal immune cells (e.g. DCs, B cells) to activate and effectively mediate contact with systemic immune sites [35].