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This prediction disregards the possibility that mechanisms may exist which preferentially mediate connections of one direction over the other, thus leading to asymmetric connectivity profiles.
Provincial hubs provide structure within the local community, and connector hubs mediate connections between multiple communities.
SMA appears to mediate connections between language areas in the PT brain.
We will evaluate whether, over months and years, stress-related alterations of HPA-axis function and inflammation mediate connections between URT and declines in cognitive performance.
Central actors are often seen as experts and most sought after for advice within the network while brokers can bridge or mediate connections between unlinked members.
CAMSAPs mediate connections between microtubule minus ends and adhesion proteins at epithelial adherens junctions (Meng et al., 2008), and the synaptic-localized CAMSAPs we observed may play a similar bridging role at synaptic adhesion sites.
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Betweenness centrality is the number of times that an individual sits along the shortest path between all others in the network (Freeman 1979), and represents the extent that an individual mediates connections and information.
Finally, mediating connections among genes by using gene products means that a network can operate in an "environment" of exogenous gene products that influence its dynamic behavior.
Given the importance of SH3 domain adaptors in mediating connections between proteins at adhesion sites [37] we undertook a human proteome-wide SH3 domain phage-display screen using the cytoplasmic domain of β-DG as an affinity ligand, in order to identify potential adaptor proteins.
Whole brain data will be acquired and analysed for derivation of fractional anisotropy measures of white matter integrity and tractography of selected axonal tracts mediating connections between limbic and frontal regions of interest.
If Drosophila Marf mediates connections of mitochondria to ER and if this activity is required for ecdysone synthesis, expression of human MFN2 (Dorn et al., 2011) in the RG may rescue the loss of LDs, alleviate the bouton morphology defects and restore 20E levels in Marf mutants.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com