Sentence examples for mediate cleavage of from inspiring English sources

We designed a truncated RNase P-associated EGS molecule to specifically recognize the U5 region of HIV-1 mRNA and mediate cleavage of hybridized mRNA by the RNase P enzyme.

Small interfering RNAs (siRNAs) mediate cleavage of specific, complementary mRNA sequences and thus regulate gene expression.

Argonaute (Ago) proteins are part of the RISC and mediate cleavage of target mRNAs [ 10, 11].

Our in vitro experiments showed that HD PMNLs can mediate cleavage of VE-cadherin from endothelial cells.

These latter caspases mediate cleavage of proteins that are essential for cell viability, resulting in morphological hallmarks of apoptosis.

HtrA2 not only counteracts the XIAP-caspase interaction but is also reported to mediate cleavage of the protein yielding fragments of 30 45 kDa.

Nani, R. R., Gorka, A. P., Nagaya, T., Kobayashi, H. & Schnermann, M. J. Near-IR Light-mediated cleavage of antibody-drug conjugates using cyanine photocages.

However, when the fusion protein of EspZ with β‐lactamase (EspZ-TEM) translocates into HeLa cells via the T3SS of WT EPEC, it mediates cleavage of CCF2‐AM, which induces a shift from green to blue fluorescence (460 nm).

Designed to simulate miRNAs, small interfering RNAs represent a powerful genetic approach to potently inhibit gene expression by mediating cleavage of the intended mRNA target.

Further studies suggested that the RF1 protein mediates cleavage of the dicistronic mRNA by binding to the intergenic region, and the processed orf79 transcripts are degraded and unable to associate with ribosome.

Finally, we systematically compared Josephin-mediated cleavage of K48-linked polyUb chains of increasing length.