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Vitronectin (VN) is a multi-functional glycoprotein best known for its effects on cell attachment and spreading, but has more recently been shown to mediate cellular responses to growth factors.
The G protein-coupled receptors are a superfamily of more than 1000 distinct cell membrane receptors that share a common heptahelical architecture and mediate cellular responses to a diverse array of extracellular stimuli, from neurotransmitters and peptide hormones to odorants and photons of light.
Transcription factors mediate cellular responses to environmental and physiologic stimuli and intracellular signaling cascades.
In vertebrates, Drosophila, and Caenorhabditis elegans, FoxO transcription factors mediate cellular responses to stress, including oxidative stress and dietary restriction.
Targets of tasiRNAs include the AUXIN-RESPONSE FACTOR proteins ARF2, ARF3/ETTIN and ARF4, which mediate cellular responses to the phytohormone auxin [20], [21], [22].
The above studies demonstrated that TLR2 can mediate cellular responses to M. pulmonis infection, but there is a possibility that other receptors, independent of TLR2, could similarly mediate cytokine responses.
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The production of Th1 is induced by interleukin-12 (IL-12), and Th1 effector cells can produce interferon-γ (IFN-γ) and mediate cellular response against intracellular pathogens.
Here we sought to systematically evaluate the basic molecular components and main pathways that govern and mediate cellular response initiated within human CD34+ cells to etoposide-induced apoptosis.
This disparity did not lead to differences in cell death, indicating that jnk2 expression does not mediate cellular response to DSBs but rather is specific to cell death in response to cell cycle initiation.
Hypoxia-inducible factors (HIF1α and HIF2α) mediate cellular response to hypoxia, which are usually induced under hypoxic condition.
Downstream to drug-target interactions proteins that mediate cellular response to CIGB-552 treatment were identified by a comparative proteomic experiment including time series (40 min, 2 h, and 5 h).
More suggestions(15)
mediate cellular movements
mediate transcriptional responses
mediate plastic responses
mediate many responses
mediate adaptive responses
mediate cellular effects
mediate humoral responses
mediate glucocorticoid responses
mediate cytokine responses
mediate inhibitory responses
mediate hyperinflammatory responses
mediate cellular functions
mediate stomatal responses
mediate neurobehavioral responses
mediate immune responses
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