Sentence examples for mediate cellular resistance from inspiring English sources

Thus, this result indicates that a decrease in the catalytic activity of the TPI enzyme mediate cellular resistance against oxidative stress caused by diamide treatment.

The MRP1 mediates the cellular efflux of various xenobiotics including heavy metals and mediates cellular resistance to heavy metals.

As shown in Figure 3c, sorafenib mediated cellular resistance to EMT in a dose-dependent manner.

In addition, SIRT3 mediates cellular resistance toward various forms of stress by maintaining genomic stability and mitochondrial integrity.

Th1 cells mediate cellular immunity and further regulate inflammation responses.

However, as FOXO factors also mediate cellular stress resistance, they might also increase resistance to chemotherapeutics.

Indeed, numerous studies suggest a close correlation between signalling events mediating cellular anoikis resistance in vitro and those mediating metastatic potential in vivo (Yawata et al, 1998; Zhu et al, 2001; Douma et al, 2004; Berezovskaya et al, 2005).

Based on these findings, we propose that cellular resistance to the cytotoxic effects of CENUs is mediated by O6-methylguanine-DNA methyltransferase and that DNA repair may also modify the mutagenic and carcinogenic properties of CENUs.

Here, we add to the knowledge of the role of CLRs in mediating possible immune activation and resistance in vivo to the helminth T. crassiceps, which may mediate cellular activation via tyrosine phosphorylation.

Mechanistically, high levels of BRC4 suppress double strand break-induced homologous recombination, inhibit the formation of RAD51 recombination repair foci, reduce cellular resistance to DNA damaging agents and induce a G2 damage checkpoint-mediated cell-cycle arrest.

Reactive oxygen species mediate cellular signaling and neuropathologies.