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The rational design of intracellular drug delivery vehicles requires an increased understanding of the elaborate systems that mediate cellular communication and coordination with the extracellular environment without inflicting on the integrity of the cell.
In the adult nervous system, neurotransmitters mediate cellular communication within neuronal circuits.
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Exosomes are 50 90 nm extracellular membrane particles that may mediate trans-cellular communication between cells and tissues.
G-proteins play a central role in cellular communication mediating the cell response to numerous hormones and neurotransmitters.
This technique makes it possible to design model systems to study cellular communication mediated by the diffusion of soluble factors within 3-D matrices.
They often are packaged with roadside-assistance services that incorporate two-way cellular communication.
Figure 1 Cellular communication in bacteria.
Reactive oxygen species mediate cellular signaling and neuropathologies.
These nuclear receptors control expression of proteins that mediate cellular cholesterol release including apoE.
For cellular communication systems, the scalability requirement is challenging.
Therefore, cellular communication and the relay-assisted D2D communication should be jointly investigated and analyzed.
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