Sentence examples for mediate cellular apoptosis from inspiring English sources

Processing of oxygen generates ROS which are involved in intracellular signalling pathways that mediate cellular apoptosis.

Two major pathways are known to mediate cellular apoptosis, death receptor-dependent (extrinsic) and mitochondrial (intrinsic) pathways.

Having demonstrated that the nanoworms are specific for CD20 and efficiently mediate cellular apoptosis, their potential therapeutic applications were probed in Raji xenografted athymic nude mice.

How ERK1/2 mediates cellular apoptosis remains poorly understood, but it appears that this may occur at different levels (Zhuang and Schnellmann, 2006).

To further study the cause of the mitochondrial shape change during stress, calcium, which is an initiator of mitochondria mediated cellular apoptosis was measured after rotenone treatment.

There were many biochemical changes in the brain of patients with AD, for example, the oxidative stress and mediating intrinsic cellular apoptosis.

Stat3 has been defined as an oncogene in light of its ability to mediate cellular transformation and block apoptosis [ 9].

Brk appears to predominantly mediate cellular survival/resistance to involution-associated apoptosis in this model.

Therefore, SFN-induced cellular apoptosis is mediated, at least in part, by epigenetic modulation of CTCF binding to the hTERT regulatory exonic region and regulation of hTERT expression in human breast cancer cells is highly responsive to SFN treatments.

Cellular apoptosis is mediated by a fine balance of pro- and anti-apoptotic proteins in cells.

Moreover, both acylated and unacylated forms of ghrelin have been shown to bind to common sites on cardiomyocytes and endothelial cells mediating similar signals to inhibit cellular apoptosis [ 10].