Sentence examples for mediate cell apoptosis from inspiring English sources

Although BCL2L11 is well known to mediate cell apoptosis (Hagenbuchner et al., 2012; Luo and Rubinsztein, 2013; Dai and Grant, 2015), its expression pattern and the biological role in cancer have not been detailedly described yet.

NF κB signaling can also engage the Caspase signaling pathway to mediate cell apoptosis.

A number of studies have suggested that AGEs mediate cell apoptosis and may play an important role in the pathogenesis of biophysical disorders [ 4, 6].

Previous studies showed that the RGD peptide has the ability to mediate cell apoptosis [ 41], in which cell adhesion plays an important role.

Several interleukins (IL-1α, IL-17RB, IL-18) and TNF have been reported to mediate cell apoptosis and death [ 34- 36], although whether this transcriptional upregulation results in damage to the alveolar macrophage is yet to be determined.

In particular, one potential mechanism of calcium-mediated cell death suggests that calcium overload results in mitochondrial dysfunction leading to mitochondrial calcium overload and activation of caspases that mediate cell apoptosis (Ichas & Mazat, 1998; Thibault et al., 1998; Begley et al., 1999).

BCL2L11 belongs to the BCL-2 family, and acts as a central regulator of the intrinsic apoptotic cascade and mediates cell apoptosis.

OPN is well known in the literature as a survival factor that mediates cell apoptosis under certain pathological stresses.

In the lipid rafts, Fas interacts with Fas-associated death domain (FADD) and Caspase-8 to form death-inducing signaling complex (DISC) and thus mediates cell apoptosis.

In the present study, with a series of cell lines deficient in cell death receptors, we demonstrated that upon avicin D treatment, Fas translocates to lipid rafts, where it associates with Fas-associated death domain (FADD) and Caspase-8 to form death-inducing signaling complex (DISC), and thus mediates cell apoptosis.

STAT1 also mediates cell apoptosis by cisplatin in coordination with the cell-cycle regulator p53.