Sentence examples for mediate cargo internalization from inspiring English sources

However, the clinical success of such an approach depends on the selection of appropriate ligands lacking immunogenic potential with the ability to mediate cargo internalization by the target cell (Allen 2002).

More recently, Eps15 was also reported to play an important function in coupling cargo internalization to clathrin-independent endocytosis [41].

The cellular concentration of muniscins regulates clathrin-coated structure organization and dynamics and, thereby, the efficiency of cargo internalization.

Additionally, nona-arginine is a cell penetrating peptide (CPP) that supports cargo internalization, including both antigens and adjuvants.

Sar1-GTP recruits Sec23/Sec24; this inner layer of COPII is thought to mediate cargo capture.

NEC components are also likely to mediate cargo selection (Funk et al., 2015).

Precisely how these morphologically-distinct coats are formed, and whether all are functionally equivalent for selective cargo internalization is still disputed.

Only the mutation that resulted in a profoundly protease hypersensitive complex (μE306K) increased cargo internalization with high significance in fcho-1 mutants.

Microglia mediate Aβ internalization through a nonsaturable, fluid phase macropinocytic mechanism.

Here we studied the endocytic processes that mediate cell internalization of the CGTs.

58 In contrast to TLR, CLR can mediate antigen internalization.