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Integrins α3, α4 and α7 mediate binding to laminins, while α2 integrin binds to collagen, and integrin αVβ8 is an RGD receptor (reviewed in [ 32]).
While the heterodimers α2 β1 and α6 β1 mediate binding to laminin, α4 β1 and α5 β1 predominantly bind to fibronectin [ 47].
IQGAPs are multidomain molecules that contain several protein-interacting motifs which mediate binding to target proteins.
These residues are predicted to mediate binding to proteins bearing a region called a PDZ domain.
Moreover, RCL appears to mediate binding to a cell surface receptor that promotes cell adhesion to type I collagen and fibronectin [12, 13].
Both structures serve to mediate binding to nuclear transport proteins.
These regions were originally identified because they mediate binding to F-actin in vitro.
Thus, sasC does not mediate binding to these extracellular matrix proteins or to activated platelets.
These epitopes do not contain anchor aa that mediate binding to the MHC groove.
In addition, an individual domain or binding site can mediate binding to more than one protein.
Membrane proteins that mediate binding to endothelial cells are exposed to the host's immune system.
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