Sentence examples for mediate apoptosis of from inspiring English sources
Of note, TNF α/TNFR1 autocrine/paracrine signaling has been implicated to mediate apoptosis of Smac mimetic at lethal concentrations.
In one report, TNF-α has been reported to mediate apoptosis of human osteoblasts in response to HIV gp120.
Additionally, Granzyme A and B are serine proteases that mediate apoptosis of virus-infected cells and IL1RA and IL17F act as proinflammatory cytokines.
Acting as primary coordinators of the apoptotic processes, reactive oxygen species (ROS) generated by NTP can mediate apoptosis of mammalian cancer cells by mitochondrial dysfunction.
We refer to this region as Death Domain-1 (DD1) since it is necessary and sufficient to mediate apoptosis of breast cancer cells.
This suggests that in addition to the P2Y2-receptor triggered [Ca2+]i-increase other signalling pathways may mediate apoptosis of oesophageal cancer cells in response to ATP.
On the other hand, c-Cbl has been shown to mediate FGFR2-mediated apoptosis of osteoblasts by downregulating α5 integrin and reducing cellular attachment 11.
The leukocyte specific protein 1 or LSP1 is a multi functional protein involved in such divers biological processes as the regulation of neutrophil motility, chemotaxis, adhesion and membrane immunoglobulin M (mIgM) mediated apoptosis of B-lymphocytes.
In vitro experiments have reported that CD4-independent interaction of CXCR4-tropic HIV mediates apoptosis of breast cells, apparently requiring no CD4 expression or interaction to mediate conformational change of HIV and occurring without evidence of in vitro or ex vivo breast cell infection by HIV [10].
Accumulating evidence shows that loss of intracellular K+ ions through enhanced delayed rectifier K+ channel (mainly Kv2.1 channel) mediates apoptosis of cortical neurons induced by a variety of treatments, such as serum deprivation, exposure to staurosporine or β amyloid peptide fragment, etc. [23], [25].
Moreover chronic extrinsic cervical spinal cord compression leads to Fas-mediated apoptosis of neurons [ 90].
