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Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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mediate an increased

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "mediate an increased" is not correct in standard written English.
It seems to be an incomplete expression and lacks clarity without additional context. Example: "The goal is to mediate an increased understanding between the two parties."

⚠ May contain grammatical issues

Science

Human-verified examples from authoritative sources

Exact Expressions

7 human-written examples

Taking into account that MYCN and c-MYC are thought to be able to compensate for each other [29], one could speculate that OTX2 expression in early photoreceptors would mediate an increased cell proliferation in these cell in the case of failed cell cycle exit during tumorigenesis.

Elevated ROCK activity may then mediate an increased vasoconstrictor sensitivity observed in various animal models with cardiovascular dysfunction [ 10, 26, 27, 30, 31, 40].

As a logical corollary, the increased numeric exposure of coyotes to M. bovis should mediate an increased detection probability relative to sampling effort.

The variants in TCF7L2 described by Grant et al. [ 1] that mediate an increased risk of type 2 diabetes have been found to be associated with reduced insulin secretion [ 6, 7, 9, 10].

The upregulation of Hor2/Gpp2 is interesting in view of the fact that upregulation of the highly similar isogene RHR2/GPP1 was found to be a strain specific determinant (SSG) of ethanol tolerance [ 35], suggested to mediate an increased capacity for NADH oxidation.

Previous studies investigating cardiovascular effects of acute inflammation using this experimental model (Hingorani et al., 2000) demonstrate a marked reduction in endothelial reactivity to endothelium-dependent vasodilators (e.g. bradykinin and acetylcholine) suggesting that acute inflammation may mediate an increased cardiovascular risk via direct endothelial effects.

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Human-verified similar examples from authoritative sources

Similar Expressions

53 human-written examples

Combined exposure to cell-free Hb and hyperoxia mediated an increased DNA-oxidation at 6 h, whereas all insults conveyed a decrease in DNA-oxidation at 120 h.

In mice, haploinsufficiency for p27 mediates an increased susceptibility to carcinogens.

Our previous study has shown that chronic activation of endothelial TRPV1 channel, which mediates an increased Ca2+ influx and subsequent phosphorylation of PKA and eNOS.

Overexpression of this protein (termed PfACBP1) in P. falciparum cells mediates an increased resistance to the ionophores which suggests its role in calcium-dependent signaling within the apicoplast.

The hypoxia-induced immunosuppression is (at least in part) mediated by an increased endogenous adrenaline response.

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Expert writing Tips

Best practice

When intending to convey facilitation, consider using stronger verbs such as "promote", "drive", or "enable" followed by a measurable noun. For instance, instead of "mediate an increased understanding", try "promote a greater understanding".

Common error

Avoid using "mediate an increased" as it often feels incomplete. This phrase requires a clear object following it to specify what is being increased. Without this, the sentence lacks clarity and precision.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

84%

Authority and reliability

2.8/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "mediate an increased" functions as part of a verb phrase, attempting to describe a process of intermediation leading to a rise in something. However, Ludwig AI indicates that the expression is not quite correct in standard written English and lacks clarity. Therefore, it is often better to rephrase it for improved accuracy and comprehension.

Expression frequency: Uncommon

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Encyclopedias

0%

Ludwig's WRAP-UP

In summary, while the phrase "mediate an increased" appears in scientific and academic contexts, Ludwig AI marks it as not quite correct, suggesting it lacks clarity. The intent is to convey a process leading to growth, but alternative phrases such as "facilitate a greater" or "promote an enhanced" offer more precise and grammatically sound ways to express this idea. Given the need for clarity in professional and scientific writing, it is advisable to favor these alternatives to improve communication. The most authoritative sources are scientific publications.

FAQs

What's a more grammatically sound way to phrase "mediate an increased"?

Consider using phrases like "facilitate a greater", "promote an enhanced", or "contribute to a rise" depending on the intended meaning and context. These alternatives provide a clearer and more direct expression of your intended idea.

How can I use "mediate" correctly in a sentence?

Use "mediate" to express acting as an intermediary. For example, "The diplomat tried to "mediate a peace agreement"" or "Technology can "mediate access to information"".

Is "mediate an increase" a correct phrase?

While technically closer to correct usage, it's often better to rephrase for clarity and impact. Using alternatives like "facilitate an increase" or "drive an increase" can improve your writing.

What are some synonyms for "mediate" in a sentence?

Depending on the context, you can use "facilitate", "negotiate", "arbitrate", "intervene", or "reconcile" as synonyms for "mediate". The best choice depends on the specific nuance you want to convey.

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Source & Trust

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Authority and reliability

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Expert rating

Real-world application tested

Most frequent sentences: