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Although a single Ser residue in a transmembrane helix is unable to mediate a strong association of the helices, the cooperative interactions of two or more appropriately placed serine hydroxyl groups per helix has been hypothesized to allow formation of a "serine zipper" that can stabilize transmembrane helix association.
Affinity-purified antibodies against each MSP3-family member were found able to mediate a strong monocyte dependent parasite inhibition in ADCI assay in vitro (Fig. 9).
Upon re-infection, Salmonella-specific memory B cells ensure rapid antibody production but Salmonella-infected B cells also mediate a strong cytotoxic CD8+ recall response to eliminate infected cells.
Based on these facts, we ascertained that the cell stimulation could mediate a strong effect on cell proliferation and differentiation.
Further quantitative analysis was prompted by the adsorption of Magnevist (12), as the molecule lacks apparently available chemical groups that would mediate a strong interaction.
These data demonstrate that cell death and HIV-1 infection independently promote T cell capture by MDM, but combined they mediate a strong uptake signal.
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Molecular dynamics simulations demonstrated that T629 phosphorylation leads to a more rigid conformation of the SAP97 binding site and, thereby, is likely to mediate a stronger interaction with the ADAM10 cytoplasmic tail.
MGMT-P140K is a clinically relevant selection marker that mediates a strong survival advantage in hematopoietic cells exposed to alkylating agents.
Furthermore Asp29' mediated a strong hydrogen bond with oxygen atom of R1 3-phenyloxazolidin-2-one ring with the distance of 1.95Å.
While addition of cultured algae alone led to a rather small effect in fish free enclosures, the presence of fish mediated a strong increase in chlorophyll-a in enclosures with ≥10 fish m−3, probably through intense predation on zooplankton.
We found that hypoxia, but not 20% O2, mediated a strong Wnt3a-induced β-catenin transcriptional activation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com