Sentence examples for mediate a specific from inspiring English sources
In the case of ETS1 and ETS2, for example, the structure of the pointed domain can mediate a specific ERK2 interaction [ 52], consistent with the ERK2 specificity we observed in Figure 1.
In addition, although the complete role of Tetherin in mammals remains unclear, limited data show that Tetherin can (at least) mediate a specific feedback mechanism to turn off interferon production by plasmacytoid dendritic cells [8], [47].
We also begin the discussion on how a generalist odorant receptor may mediate a specific pheromone response.
3D domain swapping was proposed as an important mechanism to explain the evolution of proteins from monomeric to oligomeric conformations to mediate a specific function.
In short, a temporal and spatial activation of receptor-associated transduction/transcription factors is thought to mediate a specific signal triggered by ligand binding.
Another miRNA, miR-9/9*, has recently been linked to the molecular pathways of neural differentiation, and provides a good example in which several mechanisms of epigenetic regulation feedback on one another to mediate a specific function.
The uniqueness of the interaction with PYL8 (and with no other PYL) provides an example of receptor specificity - an ABA receptor mediating a specific sub-network of responses.
Our data indicate that Sec15 mediates a specific vesicle trafficking event to ensure proper neuronal fate specification in Drosophila.
These clones displayed a CD4+CD8dim+ (TC5) and CD4+ CD8– (TC7) phenotype and mediated a specific major histocompatibility complex class I-restricted cytotoxic activity toward Cou-LB autologous tumor cell line.
The first of two extracellular fibronectin type III (FNIII) domains of the Ihog protein mediates a specific interaction with Hh protein in vitro, but the second FNIII domain is additionally required for in vivo signaling activity and for Ihog-enhanced binding of Hh protein to cells coexpressing Ptc.
CEM/VM-1 harbors a mutated topoisomerase II gene which mediates a specific resistance to topoisomerase II inhibitors, but not general multidrug resistance [19], [20].
