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IFNα may mediate a restriction that targets the viral gag-pol.
This suggests that IFNα can mediate a restriction to HIV-1 replication in a cell specific manner.
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This suggested that clustering of tetherin might mediate a proinflammatory signal upon restriction of enveloped virus release.
America is trying to mediate a reduction in tensions, and Israel last Friday removed all age restrictions for Muslim worshippers.
Try to mediate a resolution.
Based on these data, we conclude that A3G does not mediate HIV restriction in resting T cells.
In summary, our results suggest that although a highly variable peptide likely cannot mediate control, large numbers of peptides throughout the HIV proteome are sufficiently conserved to mediate potent restriction of HIV replication.
Displacement to a region with less structural restriction led to more frequent rotation, and thus the STM probe mediated a switch between a rotating and a nonrotating porphyrin.
Together, these results indicate that FoxP1 may mediate cellular growth restriction in neuroblastoma by cell cycle control, programmed cell death and induction of differentiation.
One evident example is Sirt1, a longevity gene that mediates calorie restriction (CR) benefits (Guarente, 2013), is involved in circadian regulation (Chang and Guarente, 2014; Jung-Hynes et al., 2010).
Such effects seem predominantly mediated by restriction of energy intake.
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Justyna Jupowicz-Kozak
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