Sentence examples for mediate a plethora from inspiring English sources

Once activated, p53 is able to mediate a plethora of responses including inhibition of cellular proliferation important for tumor suppression.

Antisense RNAs (asRNAs) are common in prokaryotes and can mediate a plethora of regulatory processes, including transcription interference, RNA processing, RNA stability or ribosome binding.

The ILK, which was discovered through its interactions with the β1 integrin subunit (Hannigan et al, 1996), has been demonstrated to mediate a plethora of biological events.

P2Y1 receptors are widely distributed in the central and peripheral nervous system and mediate a plethora of effects including the modulation of voltage- and transmitter-gated ion channels (Hussl and Boehm, 2006).

In the present review, I elaborate on the current understanding of redox/oxidative mechanisms mediating the regulation of key transcription factors, particularly NF-κB, that mediate a plethora of cellular functions that regulate redox-induced and oxidant-induced lung injury.

Despite its key role in mediating a plethora of cellular signaling cascades pertinent to health and disease, little is known about the structural landscape of the proline-rich (PR) domain of Sos1 guanine nucleotide exchange factor.

Non-coding RNAs (ncRNAs) are sequence-specific regulators of gene expression, mediating a plethora of cellular responses to changing environmental conditions and morphological differentiation.

Indeed, 'non-proteolytic' ubiquitin is now appreciated to be as important as 'proteolytic', since it not only mediates a plethora of DNA repair functions but also protein sorting, cell signalling and gene expression (Fig 1).

Toxicity –both for killing the insect host and warding off bacterial and fungal competitors- is mediated by a plethora of insecticidal and bactericidal gene products [ 44].

These activities are mediated by a plethora of suggested interactions with host cell proteins, by which Nef manipulates various aspects of host cell vesicular transport, cytoskeleton dynamics and cell motility, as well as signal transduction [ 44, 64, 66, 67].

The activation of PSCs is mediated by a plethora of different cytokines such as IL6, TNFα, TGF-β, and IL10, 4,7,39 and results in an increased expression of αSMA.