Exact(3)
Pharmacological agents that mediate a persistent GABAergic conductance are of considerable interest for treatment of epilepsy.
In polycrystalline semiconductors for which grain boundaries mediate a persistent change in majority carrier concentration on super-bandgap photostimulation, the change generally involves an increase.
In addition to synaptic currents (phase current), GABAA receptors also mediate a persistent tonic current, which reflects the activation of high-affinity GABAA receptors by low ambient GABA concentration [38].
Similar(56)
In summary, brief exposure to H2O2 results in an immediate and sustained increase in the surface pool of thromboxane receptor that is capable of mediating a persistent hyper-responsiveness of the cell and suggests a highly sophisticated mechanism for rapidly regulating thromboxane signaling.
A recombinant form of this human IgM was tested in two distinct models of neurological disease with very different mechanisms of cell death: (1) a model of axonal injury mediated by a persistent picornovirus and immune attack and, (2) models of ALS driven by a mutation of a protein that is normally involved in preventing oxidative stress.
Evidence for the release of cytokines from native host tissue is found in the presence of a persistent inflammatory response, mediated by T helper 1 (Th1) cells [ 55].
One important mechanism by means of which air pollution causes lung injury is certainly the induction of a persistent inflammatory state mediated by the immune system [ 23].
Therefore the ability of SF1+ neuronal activation to implement a persistent emotion state could be mediated by other nodes in this circuitry, rather than within VMHdm itself.
In other cell types, persistent hypoxia can result in cell death [20] or mediate a shift in mediator release and disturb cell functions [21], [22].
These signals help create a persistent sensitization to pathogens (e.g., in the form of antibodies that mediate immunization).
A persistent Djokovic.
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