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One POM was also found to mediate a "heterogeneous crystal formation".
However, proinflammatory cytokines mediate a heterogeneous hepatocyte response to cholestatic stimuli, with selective hepatocyte down regulation in the periportal zone [ 96].
Recently it has been shown that different drug classes mediate a heterogeneous effect on stroke through variable effects of blood pressure visit-to-visit variability [ 65] and visit-to-visit variability is an independent risk factor for vascular events.
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At the single-cell level, Th2 cytokine secretion was mediated by a heterogeneous population of NKT cells (Figure 5D).
To determine whether pre-treated TregKIF were also unable to prevent rejection mediated by a heterogeneous population of effector T cells, 1×105 CD25−CD4+ T cells were adoptively transferred into CBA-RAG−/− recipients alone or together with Treg or TregKIF at a ratio of 1∶1.
In vivo metabolic transformation of lupus-inducing drugs to reactive products explains how a heterogeneous set of drugs can mediate the same disease syndrome.
Nicotinic acetylcholine receptors (nAChRs) constitute a heterogeneous family of ion channels that mediate fast synaptic transmission in neurons.
The inflammatory myopathies (IMs) are a heterogeneous group of diseases characterized by muscle degeneration mediated by inflammatory and immune-mediated processes.
More recently, the cell-in-cell structure formation is demonstrated to be able to promote clonal selection and human tumor evolution mediated by cell competition, a mechanism evolved to eliminate less fit cells from a heterogeneous cell population.
Thus, a disorder dominated by a heterogeneous model is one in which many relatively rare but more highly-penetrant pathogenic variants mediate risk for the disease in the affected population.
We hypothesize that the harmful effect of IMHP compared to HP enteral nutrition in a heterogeneous group of critically ill patients is limited to the medical critically ill patients and mediated by an early increase in (epa + dha)/lcf ratio.
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CEO of Professional Science Editing for Scientists @ prosciediting.com