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We thus concluded that activation of Epo-R could mediate a fine regulation on Kit expression.
Apart of these plasmid-encoded regulatory components, a number of host factors (such as σ, σ, σ, σ, IHF and HU) and global regulators (Crc, PtsN, TurA, PprA, ppGpp; [ 25]) mediate a fine tuning of the system to a large number of environmental signals.
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This is mechanistically mediated through a fine control of lysosomal proteolytic activity that was previously unappreciated.
Cellular apoptosis is mediated by a fine balance of pro- and anti-apoptotic proteins in cells.
Increased TNF-α-induced apoptosis would be also counterbalanced by the anti-inflammatory actions of the peptide, possibly mediated by a fine regulation of serine-threonine kinase 1 (RIP-1) ubiquitinization and caspase signaling [ 38].
Recent modelling studies suggest that the rhythmic synchronization in the gamma range may be mediated by a fine balance between N-methyl d-aspartate and α-amino-3-hydroxy-5-methylisoxazole-4-propionate postsynaptic currents, whereas other studies have highlighted the possible contribution of the neuromodulator acetylcholine.
They often walk a fine line between mediating and seeming to condone criminal activity.
The activity of NK cells is controlled by a fine balance of inhibitory and activating signals mediated by a complex set of different receptors.
To maintain bone mass and bone quality, osteoclast bone resorption is tightly coupled with osteoblastic bone formation during bone remodeling, which requires a fine regulation by humoral factors or molecules mediating the communication among these two types of bone cells.
A fine judgment indeed.
A fine admonition.
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