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Exact(5)

Alternatively, sampling of the stimulus across the electrosensory array could mediate a direct turn towards the source.

Consistent with this lack of conservation of the motifs that mediate a direct interaction of yeast Abp1p with the Arp2/3 complex [26], we did not observe any direct binding of Abp1 to the Arp2/3 complex in a variety of biochemical experiments, including affinity purifications with different immobilized Arp2/3 complex components and yeast-two hybrid analyses (data not shown).

However, because ASNA1 interaction with VAPB was fairly robust, we proceeded to search for a potential FFAT motif in any of the TRC subunits that could mediate a direct interaction with VAPB.

Further, DNA recognition by MsqA can be attributed completely to specific residues of the recognition helix, which mediate a direct readout of the promoter DNA sequence (Brown et al. 2011).

Biochemical and transcriptional studies will now be necessary to determine if the identified eh1-like motifs mediate a direct physical interaction with Groucho corepressors to confer transcriptional repression activity.

Similar(55)

Thus, in vivo data in this study support previous in vitro findings that PilC1 mediates a direct interaction with epithelial cells [22].

SplicePredictor mediated a direct splice alignment of this protein with the Helitron sequence and detected 10 exons spanning the conserved peptidase domain within the element (data not presented).

It is possible that an active participation of muscles in the immune response is a general phenomenon, but we have so far failed to identify a Drosophila cytokine that mediates a direct signaling from muscles to hemocytes.

The absence of vascular dcc expression challenged our initial model in which Dcc mediates a direct pro-angiogenic effect of Netrin 1a, and led us to consider an alternative model.

Together, these previous data suggested that insulin signaling mediates a direct and/or indirect protection of the endothelium and the cardiovascular system, but that this is antagonized by concomitant pronounced hyperglycemia.

However, ABCD3 was estimated to be about 45 times less efficient than ABCD1 at mediating a direct or indirect transport of C26:0-CoA, across the peroxisomal membrane [15], which provides an explanation why endogenous ABCD3 is unable to rescue the metabolic defect in X-ALD patients.

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