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Per-patient SI level is defined by the median value within each timescale.
The scatter plots display the following information: blue points indicate individual pixel values, open circles represent the median value within each of ten bins evenly spaced along the horizontal axis (these are intended to assist in visualization and do not impact model fit), lines are the best fit polynomials for the data being compared.
Pretreatment EPCA level was used as a continuous variable, which was dichotomized at the median value within the cohort.
They were subsequently converted to the intermediate geography scale by computing the median value within each IG.
First, we calculated Ka and KS values for the individual genes and estimated the median value within each group.
We conducted trend tests using the median value within each tertile of U-Cd as the score variable.
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To test for linear trends over the quintiles, median values within quintiles were calculated and evaluated as a continuous variable using linear regression analysis.
Tests of linear trends across increasing quartiles of resistin levels were conducted by assigning the median values within quartiles treated as a continuous variable.
The log2-transformed ratios of Alexa-647 to Alexa-555 (not background corrected median values) underwent within-slide normalizations using weighted loess with default parameters.
Moreover, at 85% we found narrower confidence intervals both for the median values and within-session variation than at 10% contrast.
There is more variability for VEI 7 and 8 but the median value is still within the same magnitude range.
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