The lines indicate the median values estimated by bootstrap sampling (n = 20 for each of 41 intervals in 104 108) based on the assumption that read counts in genome-wide bins follow a multinomial distribution.
In these analyses, the mutation rate was fixed as the median values estimated from the previous BEAST phylogenetic analyses.
The median value for estimated tissue YM was selected due to the non-normality of individual measurements.
Time-to-event (PFS, OS, and duration of response) distribution and median value were estimated using the Kaplan Meier product limit method.
As <50% of the people treated with two or more OADs had treatment intensified after 7 years (i.e., they remained in poor glycemic control for >7 years before intensification of treatment), no exact median value was estimated.
When variance terms are not included (e.g., the parameter is a fixed effects parameter), that parameter can be considered to have complete shrinkage because only the median value is estimated (Between-subject variability section).
When parameter estimates calculated from data pooled among strains or lines of the same broodstock source were available, the estimate from the pooled data was used instead of calculating a median value, and individual estimates were discarded.
The median value for point estimates of heritability for morphometric characters, length, and weight was 0.52 in this study, a value higher than the median value of 0.29 observed from a meta-analysis of heritability for all morphological characters (including morphometric characters, length, weight) across salmonid species [41].
The median value of pairwise estimates between VIA-VIB is 0.73 (data not shown) and is close to the values of 0.71 reported by Schlueter et al. (2004) and of 0.57 reported by Pfeil et al. (2005).
Interestingly, the median NRS of estimated acceptable pain of our patients was similar with the median value to the estimated tolerable pain levels reported by Gerbershagen and colleagues.
