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The Wilcoxon test was preferred over the median test when one or more observations were "off scale".
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Compounds 13 and 14g were proved to be the most potent compounds of this series with relatively low toxicity in the median lethal dose test when compared with the reference drug.
Compounds 9a, 9b, 12a and 7a showed the highest anticonvulsant activities of this series with relatively low neurotoxicity and low toxicity in the median lethal dose test when compared with the reference drugs.
SI variability is compared using the Kolmogorov-Smirnov test, because it has more power to detect differences in the shape of distributions than the rank-sum test when median values are similar.
Continuous variables such as CD4 counts were analyzed with Mann-Whitney U test when medians were compared.
bNon parametric test of the median or Chi-square test or Fisher's exact test, when appropriate.
Differences in the median between groups were computed using the Mann Whitney U test when two groups were compared and the Kruskal-Wallis analysis of variance test when more than two groups were compared.
Continuous variables were summarized by means or medians and compared with the Student t-test or a nonparametric test, when appropriate.
Data from PCR and ELISA analysis (expressed as median (25%-75% quartiles)) were tested using Student's t-test or Mann-Whitney rank sum test when appropriate.
Mood's median test was used with R76.
Median test was applied.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com