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Next, we explored the relationship between GC% and median target coverage for both capture experiments.
Targets with higher amounts of GC% have lower amounts of median target coverage for both capture experiments and both types of DNA, as described above.
For the corresponding WGA DNA, targets in the first (GC% less than 38%) and fourth bins have a similar distribution of median target coverage.
Targets were placed in the appropriate bin and within each bin, a box plot of median target coverage was made for genomic and WGA DNA, as shown in Figure 1.
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Figure 3 shows the median number of variants discovered as a function of average target coverage for SNPs and INDELs, for each capture experiment.
Target coverage.
b Target coverage percentage.
d Target coverage percentage.
Definition 2. Target coverage graph.
Target coverage requirement is application specific.
There have been a great number of works on area coverage, target coverage and barrier coverage.
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