Sentence examples for median sequence conservation from inspiring English sources
The median sequence conservation was between 3.06 and 4.32, with a majority of 3.06.
Prediction score and median sequence conservation, respectively, are indicated in brackets.
SIFT scores and predictions in parentheses should be interpreted with caution because the median sequence conservation score was >3.25.
No SIFT median sequence conservation score reached this cutoff, indicating that the aligned sequences were diverse enough for confident prediction of substitutions that should affect protein function.
We created an alignment using PSI-Blast, with median sequence conservation at the prediction sites of 2.62, except at the first amino acid change where it was 3.09.
A SIFT median sequence conservation score cutoff of 3.25 was used to measure the diversity of the sequences used for prediction, and a score greater than 3.25 could indicate that the prediction was based on closely related sequences.
In order to enrich for functional regions, we masked subsequences based on below-median sequence conservation levels across 18 Euarchontoglires.
Network reconstruction for Micropia clustered the sequences of D. yakuba, D. melanogaster, Z. camerounensis, Z. davidi, Z. indianus and Z. africanus with central median vectors, suggesting that high sequence conservation was not due to HTs involving the species analyzed, but probably one or more donor species not sampled.
Secondly, besides sequence conservation they depict a conserved secondary structure.
Sequence conservation of 3′UTRs was measured as median phyloP scores (Pollard et al., 2010) across all bases in the most used UTR form for 3′UTR sequence alignments across 24 Drosophila species (using the D. melanogaster UTR co-ordinates).
Analysis of sequence conservation identified 354 elements that are conserved.
