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In cases where C represents the concentration of causative agent (e.g., in the medium of a cell culture), C m is the median effective concentration which, for instance, would be the median lethal concentration (LC50) if lethality were the biological effect of interest.
Median lethal concentration (LC50) of each insecticide was first determined.
Determination of the median lethal concentration (LC50) from bioassays based on Artemia salina and Lactuca sativa indicators was performed.
At the levels evaluated in the study, none of the growth factors had a significant effect on the median lethal concentration of PCC 7120#11 against An.
The median lethal concentration in sediment (LC50) of ZnO was 763 μg g−1 and 868 μg g−1 for CuO ENPs.
Only ZnO caused significant adverse effects of all MO particles tested, and only when prepared in pure water (point estimate median lethal concentration = 3.5 9.1 mg/L).
A 4-day exposure of 57-day old juveniles resulted in a total ammonium (NH4+ N) median lethal concentration (LC50) of 13 mg/L, and a corresponding un-ionized ammonia (NH3) LC50 of 147 μg/L.
It was found that the overall toxicity of Pb in the system containing NPs was greater than that of Pb alone, as indicted by the reduced median lethal concentration (LC50) of soluble Pb.
Results showed that n-TiO2 alone was not toxic when the concentration was less than 400 mg/L and that the 24-hour median lethal concentration (LC50) of As V) alone was 3.68 ± 0.22 mg/L.
LD50 determinations provide the median lethal concentration of a test compound and information in terms of the dose-response relationship, clinical signs of toxicity, and gross and histopathologic findings.
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A toxicological bioassay, the larval immersion test, was used to determine and compare the median lethal concentrations (LC50) and 90% lethal concentrations (LC90) of ivermectin for the Mozo and Juarez strains.
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