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In such cases, the inter-individual toxicokinetic variability sub-factor should be equal to the ratio of the furthermost tail of the distribution (protecting 95 or 99% of the sensitive subpopulation) and the median for normal healthy individuals.
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Maternal plasma miRNA concentration was expressed as multiples of the median (MoM) for normal pregnancies.
The median IRSs for normal and cancerous breast tissues showed no statistically significant difference.
The median values for Normal, CF1, and CF2 groups were 0.738, 0.789, and 0.792, respectively.
The median values for Normal, CF1, and CF2 groups between the WGA methods are 0.046, 0.055, and 0.046, respectively.
In this step, maternal plasma miRNAs concentrations were expressed as multiples of the median (MoM) for normal pregnancies.
HDAC11, the only member of class IV, had the lowest median value for normal brain tissue (3.67) and the highest for glioblastoma (1.02).
For genes overexpressed in tumours, expression levels were calculated relative to the median values for normal tissue, and vice versa for genes expressed at higher levels in normal tissues.
The G6PD quantitative spectrophotometric assay from capillary and venous blood was used as the reference assay; the G6PD median value for normal males was calculated using the data from 26 G6PD-normal males, and the respective 20%, 30%, and 40% thresholds were used to assess performances of qualitative tests.
A z score of ≤−2 indicates that a child's WAZ, WHZ or HAZ is 2 SD below the age- and gender-specific median for the normal population, and 3 SD below the median cut-off if the z score is ≤−3.
2 Briefly, the adjusted G6PD median activity value for normal males was calculated (excluding males with severe G6PD deficiency defined as ≤ 10% of the G6PD median value for all males in the study population), and different cutoff levels of activity were defined (i.e., 10%, 20 %, 30, and 60% of the andusted male median value).
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