Most 79-933 %, depending on the tissue) testis xUTRs are also present in somatic tissues; the unannotated regions have median expression levels 0.18-0.33 fold that of the annotated expressed mRNA (Additional file 1: Figure S3).
We thus focused on the set of probes with significantly higher and lower expression levels in adult liver compared to fetal liver (from the previous section "The transcriptome of the developing liver"), and formed a matched set of probes that were not differentially expressed between the two groups but displayed similar median expression levels and standard deviations in the adult liver samples.
We compared the top 400 highly expressed EIGs against the top 600 EVGs, as they have very similar median expression levels (median RPKM = 266 and 269, respectively).
In acute lymphoblastic leukaemia patients, higher than median expression levels of HDAC3 were associated with a significantly lower 5-year event-free survival [34].
On the contrary, genes associated with promoter DNA methylation or H3K27Me3 alone and in combination had lower median expression levels (Figure 6A middle panel).
An additional cell-line specific normalization step was performed in which median expression levels for each protein was first determined and then subtracted from individual RPPA experiments.
The genes associated with promoter H3K4Me3 methylation displayed higher median expression levels even if DNA methylation or H3K27Me3 marks co-existed.
According to our QRT-PCR data on the pregnancy-related whole blood markers such as DEFA4, the median expression levels of these genes were much higher than that of the placenta-derived transcripts in whole blood (Figures 2 and 4).
Median expression levels were used to define the groups.
While genes with HP inheritance patterns show the highest median expression levels, genes with LPMP and LP patterns show relatively low median expression levels.
The median expression levels among the various categories allowed quantification of these differences.
