Sentence examples for median effect plot from inspiring English sources

The median effective dose (IC50) was determined for the pure phytochemical compounds and the leaf extract from the median effect plot of log (fa/ fu) versus log (dose), where fa is the fraction affected and fu is the fraction unaffected by the treatment.

Analysis was performed using the software CalcuSyn (Biosoft, Ferguson, MO, USA) (see Figure 3 for CI values), which allows automated simulation of synergism and antagonism at all dose and effect levels and displays the methods of Chou and Talalay [20], including median effect plot and CI values.

Combination effects were analyzed by median effect plot analysis.

R denotes the coefficient of determination of the linear regression in the median effect plot.

The interaction between AEE788 and 4-OH tamoxifen or letrozole was analysed by the median effect plot method described by Chou and Talalay (1984).

The log version of the above equation gives the median effect plot where log⁡(f a / f u ) is plotted on the y-axis and log⁡⁡(D) is plotted on the x-axis.

Combination index values were derived from variables of the median effect plots and statistical tests were applied (unpaired, two-tailed Student's t-test) to determine whether the mean CI values at multiple effect levels were significantly different from CI=1.

Combination index (CI) values were derived from parameters of the median effects plots, and statistical tests were applied (unpaired, two-tail Student t test) to determine whether the mean CI values at multiple concentrations were significantly different from CI = 1.

In the computational analysis for either one of the four drugs (RAL, TDF, L-000870812, or ZDV), the linear correlation coefficient (r values) of the median-effect plot or for their constant ratio combinations ranged from 0.92 to 0.99 (data not shown), matching the law of mass-action.

The combined effect was demonstrated to be synergistic using the isobologram and median-effect plot analyses.

IC50 values (in ng·ml−1) were determined using a median-effect plot [ 20].